MASS SPECTROMETRY

The Mass Spectrometry Facility has one GCMS, one MALDI-MS, one DART-MS, one ICP-MS, one LC-TOF, two LC-QTOF, two LC-triple Quads, and one LC-orbitrap instruments for qualitative and quantitative analyses. The facility is located in 1434 Molecular Science Building (MSB). Members of the UCLA community, other academic institutions, and commercial enterprises may use the mass spectrometers after training by the Mass Spectrometry Laboratory staff.

All users will have their grants recharged for use of the mass spectrometers. Users from Departments other than Chemistry and Biochemistry must request a 6-digit recharge account prior to use of the spectrometers (download application form).

To learn more, please contact the mass spectrometry staff.

Small molecule mass measurement:

Agilent GC-Ion trap, Agilent GC-TOF, Waters LC-TOF, Thermo DART-Orbitrap, Agilent 6545 LC-QTOF

Small molecule quantification with MRM mode:

Sciex 4000 QTRAP QQQ, Sciex API 4000 QQQ

Trace metal quantification:

Agilent QQQ ICP-MS

Peptides and intact proteins analysis:

Bruker MALDI-TOF, Agilent 6530 LC-QTOF, Thermo Q Exactive plus Orbitrap

Metabolomic analysis:

Thermo Q-Exactive plus Orbitrap MS coupled with Thermo Vanquish UPLC, Agilent 6545 LC-QTOF

Proteomic analysis:

Thermo Q-Exactive plus Orbitrap MS coupled with Thermo Ultimate 3000 nanoLC

Instrumentation is available for 1D and 2D gel electrophoresis.

MIC staff offer instrumentation training, analysis service, and consultation for sample preparation, experiment design, data mining, and operation of the various instruments.