Mass Spectrometry

Photo by Penny Jennings-UCLA Department of Chemistry and Biochemistry.
The Mass Spectrometry (MS) Laboratory of the Molecular Instrumentation Center at UCLA provides a wide range of sample characterization techniques for UCLA researchers, other academic institutions, and commercial enterprises:
  • MS ionization methods: Electron ionization (EI), chemical ionization (CI), matrix assisted laser desorption ionization (MALDI), direct analysis in real time (DART), electrospray ionization (ESI), and atmospheric pressure chemical ionization (APCI).
  • MS analyzers: Time of flight, quadrupole, ion trap, Orbitrap ion cyclotron resonance (FT) analyzers, and several tandem combinations of mass analyzers.
  • Gels: Equipment is available for 1-D and 2-D gels, transferring mini and mid-size gels, gel imaging, 1-D and 2-D gel analysis, spot cutting, in-gel digestion, and protein/peptide identification for a large variety of proteomics studies.
  • Consultation: Sample preparation, experiment design, gel staining, analysis of protein expression patterns, western and lectin blots, in-gel trypic digestion, data mining and operation of the various instruments.